Indications

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone. Read more

You are about to go to the ENBREL website for healthcare professionals.

This information is intended only for healthcare professionals in the US. If you are a healthcare professional, click “I agree” to continue.

I agree Cancel

Caring for yourself

In addition to following your doctor’s treatment plan, make sure you are taking care of YOU. That can include taking the time to make positive and healthy lifestyle choices and thinking about ways you can help to self-manage your condition, both physically and emotionally.

While these choices won’t necessarily impact how ENBREL works for you, they may make a difference in how your condition impacts your day-to-day activities and your outlook.

Having things like the right fitness plan and/or diet and a positive attitude can go a long way towards helping manage your condition.

Here are some tips that may help you:

Staying active

Exercising may be the last thing on your mind, especially if you are experiencing severe symptoms. But with symptom relief, you may be thinking how you can return to activities that are important to you, including exercise.

Make sure you talk with your doctor to come up with a plan to increase your physical activity together. Be sure to keep communicating with your doctor about how it’s going and what changes you can make over time.

Healthy diet

A healthy diet can go a long way. Try introducing a diet that’s low in processed foods and saturated fats and replacing them with anti-inflammatory foods like berries, cherries, and leafy greens. Remember to talk to your doctor about making any changes to your diet.

Keeping positive

Savor the little things! Celebrate the little things, from opening a jar to spending an afternoon with loved ones.

  • Don’t sweat the small stuff:

    • When symptoms are flaring or you’re not feeling well, give yourself permission to take care of yourself

  • Keep things in perspective:

    • Some days, you may get angry because things take longer to do, or you just can’t do them all together, and that’s okay. The chronic nature of your condition means there will be tough days, but take things at your own pace and don’t feel bad about it

  • Planning ahead:

    • Planning things out ahead of time can be very important when managing your condition. On your good days, take time to prepare for any bad days ahead, such as preparing future meals or working on activities that may be harder to do on your bad days

Prescription Enbrel® (etanercept) is taken (given) by injection.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections. Serious infections have happened in patients taking ENBREL. These infections include tuberculosis (TB) and infections caused by viruses, fungi, or bacteria that have spread throughout the body. Some patients have died from these infections. Your healthcare provider should test you for TB before you take ENBREL and monitor you closely for TB before, during, and after ENBREL treatment, even if you have tested negative for TB.

There have been some cases of unusual cancers, some resulting in death, reported in children and teenagers who started using tumor necrosis factor (TNF) blockers before 18 years of age. Also, for children, teenagers, and adults taking TNF blockers, including ENBREL, the chances of getting lymphoma or other cancers may increase. Patients with RA may be more likely to get lymphoma.

Before starting ENBREL, tell your healthcare provider if you:

  • Have any existing medical conditions
  • Are taking any medicines, including herbals
  • Think you have, are being treated for, have signs of, or are prone to infection. You should not start taking ENBREL if you have any kind of infection, unless your healthcare provider says it is okay
  • Have any open cuts or sores
  • Have diabetes, HIV, or a weak immune system
  • Have TB or have been in close contact with someone who has had TB
  • Were born in, lived in, or traveled to countries where there is more risk for getting TB. Ask your healthcare provider if you are not sure
  • Live, have lived in, or traveled to certain parts of the country (such as, the Ohio and Mississippi River valleys, or the Southwest) where there is a greater risk for certain kinds of fungal infections, such as histoplasmosis. These infections may develop or become more severe if you take ENBREL. If you don’t know if these infections are common in the areas you’ve been to, ask your healthcare provider
  • Have or have had hepatitis B
  • Have or have had heart failure
  • Develop symptoms such as persistent fever, bruising, bleeding, or paleness while taking ENBREL
  • Use the medicine Kineret (anakinra), Orencia (abatacept), or Cytoxan (cyclophosphamide)
  • Are taking anti-diabetic medicines
  • Have, have had, or develop a serious nervous disorder, seizures, any numbness or tingling, or a disease that affects your nervous system such as multiple sclerosis or Guillain-Barré syndrome
  • Are scheduled to have surgery
  • Have recently received or are scheduled for any vaccines. All vaccines should be brought up-to-date before starting ENBREL. Patients taking ENBREL should not receive live vaccines
  • Are pregnant, planning to become pregnant, or breastfeeding
  • Have been around someone with chicken pox

What are the possible side effects of ENBREL?

ENBREL can cause serious side effects including: New infections or worsening of infections you already have; hepatitis B can become active if you already have had it; nervous system problems, such as multiple sclerosis, seizures, or inflammation of the nerves of the eyes; blood problems (some fatal); new or worsening heart failure; new or worsening psoriasis; allergic reactions; autoimmune reactions, including a lupus-like syndrome and autoimmune hepatitis.

Common side effects include: Injection site reactions and upper respiratory infections (sinus infections).

In general, side effects in children were similar in frequency and type as those seen in adult patients. The types of infections reported were generally mild and similar to those usually seen in children.

These are not all the side effects with ENBREL. Tell your healthcare provider about any side effect that bothers you or does not go away.

If you have any questions about this information, be sure to discuss them with your healthcare provider. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see Prescribing Information and Medication Guide.

INDICATIONS

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in patients with moderately to severely active rheumatoid arthritis. ENBREL can be taken with methotrexate or used alone.

ENBREL is indicated for reducing signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis (pJIA) in children 2 years of age or older.

ENBREL is indicated for reducing signs and symptoms, keeping joint damage from getting worse, and improving physical function in adult patients with psoriatic arthritis. ENBREL can be used with or without methotrexate.

ENBREL is indicated for active juvenile psoriatic arthritis (JPsA) in children 2 years of age or older.

ENBREL is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.

ENBREL is indicated for chronic moderate to severe plaque psoriasis (PsO) in children 4 years of age or older and adults who may benefit from taking injections or pills (systemic therapy) or phototherapy (ultraviolet light).

Prescription Enbrel® (etanercept) is taken (given) by injection.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENBREL?

ENBREL is a medicine that affects your immune system. ENBREL can lower the ability of your immune system to fight infections.